Metronidazole breastfeeding side effects baby

Breastfeeding is universally recognized as the preferred method of infant feeding and is associated with decreased infant mortality, but it is sometimes abbreviated because of fear of harm to the infant from maternal medication.¹ Despite this, physicians often receive little education on supporting breastfeeding.

Comprehensive assessment can prevent unnecessary avoidance of breastfeeding, premature discontinuation of breastfeeding, or suboptimal treatment of the mother’s condition.

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This article provides information on the management of medications for common conditions during lactation.

Transfer of Medications Into Breast Milk

Medications enter breast milk through diffusion from serum, so milk concentrations depend on maternal serum drug concentrations and diffusion characteristics.

Few medications are actively transported into breast milk.^2,3 Medications generally diffuse out of breast milk as the concentration in maternal plasma diminishes. Unlike the placental transport in pregnancy, medication absorption in breastfeeding is via the infant gastrointestinal tract.

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