Insulin and glucose for hyperkalemia mechanism of action

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  • How is insulin used to treat hyperkalemia
  • What is the emergency treatment for hyperkalemia

  • Insulin and potassium shift
  • Hyperkalemia treatment protocol
  • Why do you give dextrose and insulin for hyperkalemia
  • Insulin and potassium relationship
  • Hyperkalemia treatment protocol.


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    Keywords: emergency medicine, hyperkalemia, hypoglycemia, insulin, intensive care units, length of stay

    Objectives:

    The objectives of this study were to evaluate the safety and efficacy of insulin dosing of less than 10 units versus 10 units in patients receiving hyperkalemia treatment.

    Design:

    Retrospective single-center study.

    Setting:

    Emergency department at a large academic medical center in the United States.

    Patients:

    Seven hundred adults treated for hyperkalemia with IV regular insulin between April 1, 2013, and September 27, 2018.

    Interventions:

    Patients that received less than 10 units of insulin were compared to those that received 10 units of insulin.

    Measurements and Main Results:

    Patients treated with less than 10 units had significantly lower frequency of hypoglycemia (11.2% vs 17.6%; p = 0.008).

    Reduction in serum potassium was significantly more modest in size in patients treated with less than 10 units (mean reduction 0.94 ± 0.71 mMol/L) compared with patients treated with 10 units (mean redu

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